[tracerDB] display

[Complete List]

Total tracers:		36
By Application:	Oncology	15		By Isotope:	Tc-99m	14
	Neurology	12			Ga-67/In-111	4
	Cardiology	12			I-123/I-125	17
	Nephrology	3			Tl-201	1

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Id

SPECT Tracer Database

16
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Chemical name:

125I- Iothalamate sodium

Common names:

Commercial product:

Glofil

Supplier:

Isotex Diagnostics

Target:

N/A

Mechanism:

Urinary clearance

Application:

Reported Use:

Add. Comments:

Isotope Family:

Publications:

Synthesis:

In vitro analysis:

Animal Studies:
Schnermann J, Chou CL, Ma T, Traynor T, Knepper MA, Verkman AS. Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9660-4. Lorenz JN, Schultheis PJ, Traynor T, Shull GE, Schnermann J. Micropuncture analysis of single-nephron function in NHE3-deficient mice. Am J Physiol. 1999 Sep;277(3 Pt 2):F447-53. Taylor A Jr, Lallone R. Differential renal function in unilateral renal injury: possible effects of radiopharmaceutical choice. J Nucl Med. 1985 Jan;26(1):77-80.
Clinical Studies:
Anderson CF, Sawyer TK, Cutler RE. Iothalamate sodium I 125 vs cyanocobalamin Co 57 as a measure of glomerular filtration rate in man. JAMA. 1968 May 20;204(8):653-6 Guesry P, Kaufman L, Orloff S, Nelson JA, Swann S, Holliday M. Measurement of glomerular filtration rate by fluorescent excitation of non-radioactive meglumine iothalamate. Clin Nephrol. 1975;3(4):134-8. Wiener SN, Shah YP, Mares RM, Flynn MJ. Correlation of I-125 iothalamate and tc-99m DPTA measurements of GFR using the single injection method. Clin Nucl Med. 1982 Aug;7(8):359-63. van Rossum LK, Zietse R, Vulto AG, de Rijke YB. Renal extraction of cystatin C vs 125I-iothalamate in hypertensive patients. Nephrol Dial Transplant. 2006 May;21(5):1253-6.

Examples

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