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Total tracers:   36
By Application: Oncology 15   By Isotope: Tc-99m 14
  Neurology 12     Ga-67/In-111 4
  Cardiology 12     I-123/I-125 17
  Nephrology 3     Tl-201 1

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Id SPECT Tracer Database
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Chemical name:201Tl
Common names:Thallous-201 Chloride for injection
Commercial product: 
Supplier:GE Healthcare, Bristol Myer, local radiopharmacy
Target:Cardiac metabolic elements
Mechanism:Metabolism-imaging radiopharmaceutical
Application:Oncology  Cardiology  
Reported Use: 
Add. Comments: 
Isotope Family:Tl-201  
Publications:
Synthesis:
In vitro analysis:
  • Mruck S, Pfahlberg A, Papadopoulos T, Stremmel C, Kuwert T. Uptake of (201)Tl into primary cell cultures from human thyroid tissue is multiplied by TSH. J Nucl Med. 2002 Feb;43(2):145-52.
  • Kinuya S, Yokoyama K, Li XF, Bai J, Watanabe N, Shuke N, Takayama T, Bunko H, Michigishi T, Tonami N. Hypoxia-induced alteration of tracer accumulation in cultured cancer cells and xenografts in mice: implications for pre-therapeutic prediction of treatment outcomes with (99m)Tc-sestamibi, (201)Tl chloride and (99m)Tc-HL91. Eur J Nucl Med Mol Imaging. 2002 Aug;29(8):1006-11.
  • Animal Studies:
  • Fukushima K, Momose M, Kondo C, Kusakabe K, Kasanuki H. Myocardial kinetics of (201)Thallium, (99m)Tc-tetrofosmin, and (99m)Tc-sestamibi in an acute ischemia-reperfusion model using isolated rat heart. Ann Nucl Med. 2007 Jul;21(5):267-73. Epub 2007 Jul 25.
  • Takahashi N, Reinhardt CP, Marcel R, Leppo JA. Myocardial uptake of 99mTc-tetrofosmin, sestamibi, and 201Tl in a model of acute coronary reperfusion. Circulation. 1996 Nov 15;94(10):2605-13.
  • Takehana K, Beller GA, Ruiz M, Petruzella FD, Watson DD, Glover DK. Accuracy of detection of myocardial viability and residual infarct vessel stenoses with rest Tl-201 and adenosine Tc-99m sestamibi imaging after coronary reperfusion in dogs with experimental acute myocardial infarction. J Nucl Cardiol. 2003 Jul-Aug;10(4):375-84.
  • Ruiz M, Takehana K, Petruzella FD, Watson DD, Beller GA, Glover DK. Arbutamine stress perfusion imaging in dogs with critical coronary artery stenoses: (99m)Tc-sestamibi versus (201)Tl. J Nucl Med. 2002 May;43(5):664-70.
  • Kinuya...
  • Clinical Studies:
  • Wei L, Kadoya M, Momose M, Kurozumi M, Matsushita T, Yamada A. Serial assessment of left ventricular function in various patient groups with Tl-201 gated myocardial perfusion SPECT. Radiat Med. 2007 Feb;25(2):65-72.
  • Fieno DS, Thomson LE, Slomka P, Abidov A, Friedman JD, Germano G, Berman DS. Quantitation of infarct size in patients with chronic coronary artery disease using rest-redistribution Tl-201 myocardial perfusion SPECT: correlation with contrast-enhanced cardiac magnetic resonance. J Nucl Cardiol. 2007 Jan;14(1):59-67.
  • Boundas D, Karatzas N, Moralidis E, Arsos G, Drevelengas A, Pistevou-Gompaki K, Karakatsanis C. Comparative evaluation of 99mTc-depreotide and 201Tl chloride single photon emission tomography in the characterization of pulmonary lesions. Nucl Med Commun. 2007 Jul;28(7):533-40.
  • Akaki S, Shinya T, Sato S, Kuroda M, Kanazawa S. Positive gallium-67 and thallium-201 scans in thymic rebound after chemotherapy for lymphoma. Ann Nucl Med. 2006 Feb;20(2):161-3.
  • Maki K, Okumura Y...
  • Examples
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