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Total tracers:		36
By Application:	Oncology	15		By Isotope:	Tc-99m	14
	Neurology	12			Ga-67/In-111	4
	Cardiology	12			I-123/I-125	17
	Nephrology	3			Tl-201	1

Id	Bioscan: SPECT Tracer Database
1 [details]	Chemical name: 111-Indium-diethylenetriaminepentaacetic acid-d-phenylalanine-octreotide Common names: 111-In-DTPA-octreotide; 111-In-DTPA-OC; 111-In-DTPA-d-Phe-octreotide; 111-In-pentetreotide Commercial product: OctreoScan® (Mallinckrodt) Target: Somatostatin receptor (SSR) Mechanism: Ligand binding to SSR subtypes 2 and 5. Application: Oncology   Isotope Fam.: Ga-67/In-111
3 [details]	Chemical name: 123I/125I-Iomazenil Common names: 123I/ 125I-IMZ Commercial product: Mallinckrodt Target: Central-type benzodiazepine receptors on neurons Mechanism: Receptor binding Application: Neurology   Isotope Fam.: I-123/I-125
4 [details]	Chemical name: [123I]N-(3-Fluoropropyl)-2β-carbomethoxy-3β-(4-iodophenyl)nortropane Common names: [123I]β-CIT-FP Commercial product: DaTSCAN Target: Dopamine transporter Mechanism: Receptor binding radiopharmaceutical Application: Neurology   Isotope Fam.: I-123/I-125
5 [details]	Chemical name: [2[[2-[[[3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3,2,1]-oct-2-yl]- methyl](2-mercaptoethyl)amino]ethyl]amino]ethanethiolato(3-)-N2,N2’,S2,S2]oxo- [1R-exo-exo)])-[99mTc]-technetium Common names: 99mTc-TRODAT-1 Commercial product:   Target: Dopamine transporter Mechanism: Receptor binding radiopharmaceutical Application: Neurology   Isotope Fam.: Tc-99m
6 [details]	Chemical name: [123I/]6-Iodo-2-(4´-dimethylamino)-phenyl-imidazo[1,2-a]pyridine Common names: [123I/125I]-IMPY Commercial product:   Target: beta-amyloid peptide Mechanism: Receptor binding radiopharmaceutical Application: Neurology   Isotope Fam.: I-123/I-125
7 [details]	Chemical name: 111In-Imciromab pentetate Common names: Myoscint, 111In-antimyosin antibody Commercial product: Centocor B.V. Target: Human cardiac myosin Mechanism: Antigen-binding radiopharmaceutical Application: Cardiology   Isotope Fam.: Ga-67/In-111
8 [details]	Chemical name: 99mTc-teboroxime Common names:   Commercial product: Cardiotec Target: Cardiac metabolic elements Mechanism: Metabolism-imaging radiopharmaceutical Application: Cardiology   Isotope Fam.: I-123/I-125
9 [details]	Chemical name: 99mTc-tetrofosmin, 99mTc-1,2-bis[bis(2-ethoxyethyl) phosphino] ethane. Common names:   Commercial product: Myoview Target: Cardiac metabolism Mechanism: Metabolism-imaging radiopharmaceutical Application: Cardiology   Isotope Fam.: Tc-99m
10 [details]	Chemical name: 201Tl Common names: Thallous-201 Chloride for injection Commercial product:   Target: Cardiac metabolic elements Mechanism: Metabolism-imaging radiopharmaceutical Application: Oncology  Cardiology   Isotope Fam.: Tl-201
11 [details]	Chemical name: 99mTc-sestamibi, 99mTc-methoxy-isobutyl-isonitrile Common names: 99mTc-MIBI Commercial product: Cardiolite (BMS), Cardio-Spect (Medi-Radiopharma) Target: Cardiac metabolism Mechanism: Metabolism-imaging radiopharmaceutical Application: Oncology  Cardiology   Isotope Fam.: Tc-99m
12 [details]	Chemical name: 99mTc-D-glucaric acid Common names: 99mTc-glucarate Commercial product:   Target: Glucose metabolism Mechanism: Metabolism-imaging radiopharmaceutical Application: Oncology  Cardiology   Isotope Fam.: Tc-99m
13 [details]	Chemical name: 99mTc-Mercaptoacetyltriglycine Common names:   Commercial product: 99mTc-MAG3, TechneScan MAG3 Target: N/A Mechanism: Tubular secretion and glomerular filtration Application: Nephrology   Isotope Fam.: Tc-99m
14 [details]	Chemical name: 99mTc-Dimercaptosuccinic acid Common names:   Commercial product: 99mTc-DMSA Target: N/A Mechanism: Urinary clearance Application: Nephrology   Isotope Fam.: Tc-99m
15 [details]	Chemical name: 99mTc- Diethylenetriaminepentaacetic acid Common names:   Commercial product: 99mTc-DTPA, Techescan DTPA Target: Assessment of renal function Mechanism: Urinary clearance Application: Isotope Fam.: Tc-99m
16 [details]	Chemical name: 125I- Iothalamate sodium Common names:   Commercial product: Glofil Target: N/A Mechanism: Urinary clearance Application: Nephrology   Isotope Fam.: I-123/I-125
17 [details]	Chemical name: 99mTc-Arcitumomab Common names:   Commercial product: 99mTc-IMMU-4, CEA-Scan®, 99mTc-NP-4 anti-CEA MAb Fab´ Target: Carcinoembryonic antigen (CEA) Mechanism: Antigen-binding radiopharmaceutical Application: Oncology   Isotope Fam.: Tc-99m
18 [details]	Chemical name: 5-123I/125I- Iodo-3-[2(S)-2-azetidinylmethoxy]pyridine Common names: 5-123I/ 125I-IA and 5-Iodo-A-85380 Commercial product:   Target: Neuronal α4β2 nicotinic acetylcholine receptor Mechanism: Receptor binding radiopharmaceutical Application: Neurology   Isotope Fam.: I-123/I-125
19 [details]	Chemical name: 123I/125I-Vascular endothelial growth factor Common names: 123I/ 125I-VEGF Commercial product:   Target: Vascular endothelial growth factor (VEGF) receptors Mechanism: Receptor binding radiopharmaceutical Application: Oncology  Cardiology   Isotope Fam.: I-123/I-125
20 [details]	Chemical name: 125I /123I-Annexin V Common names: 125I /123I-rh-Anx5 Commercial product:   Target: Phosphatidylserine (PS) and apoptosis Mechanism: Receptor-binding radiopharmaceutical Application: Oncology  Cardiology  Neurology   Isotope Fam.: I-123/I-125
21 [details]	Chemical name: 2'-Fluoro-2'-deoxy-5'-125I-iodo-1â-d-arabinofuranosyluracil Common names: 125I/ 123I -FIAU Commercial product:   Target: Herpes simplex virus thymidine kinase (HSV-TK) Mechanism: Functional radiopharmaceutical based on phosphorylation Application: Oncology  Cardiology  Neurology   Isotope Fam.: I-123/I-125
22 [details]	Chemical name: 99mTc-[Cys3,4,10,d-Phe7,Arg11]á-MSH3-13 Common names: 99mTc-(Arg11)CCMSH Commercial product:   Target: Melanocortin-1 (MC-1) receptor Mechanism: Receptor binding radiopharmaceutical Application: Oncology   Isotope Fam.: Tc-99m
23 [details]	Chemical name: 111In-Capromab pendetide Common names: 111In-CYT-356 Commercial product: ProstaScint Target: Prostate-specific membrane antigen (PSMA) Mechanism: Antigen-binding radiopharmaceutical Application: Oncology   Isotope Fam.: Ga-67/In-111
24 [details]	Chemical name: 99mTc-single-chain vascular endothelial growth factor Common names: scVEGF/Tc Commercial product: scVEGF, scVEGF-PEG-DOTA for site-specific radiolabeling with radionuclides by end-user Target: VEGF receptors in angiogenic vasculature Mechanism: receptor-binding, internalizable radiopharmaceutical Application: Oncology  Cardiology   Isotope Fam.: Tc-99m
30 [details]	Chemical name: l5-(p-[123I]iodophenyl)-3-R,S-methylpentadecanoic acid Common names: I-123-BMIPP Commercial product: Zemiva (Molecular Insights Pharmaceuticals, USA), Cardiodine (Nihon Medi-Physics, Japan). Target: Cardiac fatty acid metabolism Mechanism: Cardiac fatty acid metabolism Application: Cardiology   Isotope Fam.: I-123/I-125
42 [details]	Chemical name: Radioiodinated anti-TAG-72 humanized CH2 domain-deleted antibody Common names: 125I/123I-HuCC49ΔCH2 Ab, 125I/123I-CC49 Ab Commercial product: RIGS (Neoprobe Corporation, USA) Target: (Sialyl-Tn) TAG-72 Mechanism: Antibody to antigen binding Application: Oncology   Isotope Fam.: I-123/I-125
43 [details]	Chemical name: 111In-Ibritumomab tiuxetan Common names: 111In-Zevalin, 111In-2B8 MAb Commercial product: 111In-Zevalin Target: CD20 antigen on B-cell non-Hodgkin’s lymphoma Mechanism: Antibody-antigen binding Application: Cardiology   Isotope Fam.: Ga-67/In-111
44 [details]	Chemical name: 99mTc-labeled anti-tumor necrosis factor-α monoclonal antibody Common names: 99mTc-anti-TNF-α mAb, 99mTc-infliximab. Commercial product: Remicade® Target: Tumor necrosis factor-α Mechanism: Antibody-ligand binding Application: Oncology   Isotope Fam.: Tc-99m
45 [details]	Chemical name: Radioiodinated humanized monoclonal antibody A33 Common names: Radioiodinated-huA33 mAb, [125I/124I/131I]huA33 Commercial product:   Target: Glycoprotein A33 Mechanism: Antibody-antigen binding Application: Oncology   Isotope Fam.: I-123/I-125
46 [details]	Chemical name: Acetyl-lys-lys-lys-lys-lys-cys-gly-cys-gly-gly-pro-leu- tyr-lys-lys-ile-ile-lys-lys-leu-leu-glu-ser-heparin-[99mTc] Common names: P483H-99mTc Commercial product:   Target: Leukocytes Mechanism: Receptor-binding Application: Isotope Fam.: Tc-99m
47 [details]	Chemical name: Iodinated Cocaine analogue of 3 beta-phenyltropane-2 beta-carboxylic acid methyl ester. Common names: I123/I125-RTI-55, I123/I125-Beta-CIT Commercial product: Dopascan (Guilford Pharmaceuticals Inc) Target: Dopamine and serotonin transporter Mechanism: Receptor-binding radioligand Application: Neurology   Isotope Fam.: I-123/I-125
48 [details]	Chemical name: 123I/125I-labeled 2'-iodospiperone Common names: 123I/125I-2'-ISP Commercial product:   Target: D2 receptors Mechanism: Receptor-binding radiopharmaceutical Application: Neurology   Isotope Fam.: I-123/I-125
49 [details]	Chemical name: Iodinated (+/-)-exo-2-(2-iodo-5-pyridyl)-7-azabicyclo[2.2.1]heptane (IPH) Common names: Iodo epibatidine analogue, 123I/125I-IPH Commercial product:   Target: Central nicotinic acetylcholine receptors Mechanism: Receptor-binding radiopharmaceutical Application: Neurology   Isotope Fam.: I-123/I-125
50 [details]	Chemical name: Radioiodinated p-iodoclonidine Common names: p-123I/125I-iodoclonidine Commercial product:   Target: Central alpha 2-adrenergic receptors Mechanism: Receptor-binding radiopharmaceutical Application: Neurology   Isotope Fam.: I-123/I-125
51 [details]	Chemical name: 99mTc-Anti-CD3 monoclonal antibody Common names: 99mTc-OKT3 Commercial product: Orthoclone (Ortho Biotech, US) Target: CD3 antigen on human T cells Mechanism: Antigen-binding radiolabeled antibody Application: Isotope Fam.: Tc-99m
52 [details]	Chemical name: 8-[123I]iodo- l-1,2,3,4-tetrahydro-7-hydroxyisoquinoline-3-carboxylic acid Common names: [123I]ITIC, [123I]ITIC(OH) Commercial product:   Target: Amino acid transporter T system and membrane potential Mechanism: Amino acid uptake Application: Oncology  Neurology   Isotope Fam.: I-123/I-125
53 [details]	Chemical name: 99mTc-Ubiquicidin29-41 Common names: 99mTc-UBI29-41 Commercial product:   Target: Amino acid transporter T system and membrane potential Mechanism: Amino acid uptake Application: Isotope Fam.: Tc-99m

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